Skip to main content
Home
  • Home
  • Study Information
  • Sites
  • Contact Us
User account menu
  • Log in

The GEKO Study

  • Thomas Barge
    Genicular artery embolisation
    GEKO: Genicular Embolisation for Knee OA

In patients with painful knee osteoarthritis, is genicular artery embolisation effective at reducing pain in comparison to a placebo intervention?

Osteoarthritis of the knee is a painful condition that can affect daily life. In the early stages, patients often find relief from lifestyle changes and exercises. When the knee becomes very damaged, surgery may be necessary to relieve pain and improve function. In between these stages, pain can still be a big problem, and treatments like pain medications and physiotherapy may become less effective.

A new treatment has been developed which aims to relieve pain in the knee by blocking (embolising) small extra blood vessels around the knee. This is thought to also reduce the number of extra nerves causing pain because the extra nerves will not have a blood supply. Early studies show some promising results, but a larger study is needed to confirm if this treatment can effectively reduce pain in people with knee osteoarthritis. The GEKO Study hopes to find out if the treatment can help those where simple treatments no longer work, but surgery isn’t yet necessary. If successful, it could provide relief for many people suffering from knee osteoarthritis.

Recruitment

We aim to recruit 216 patients over a period of 18 months from approximately 12 sites in the UK.

Information for Patients

Patient Information Sheet V2.0 20Jun2025

Study Team

Chief Investigators: 
Professor Andrew Price 
Dr Raman Uberoi

Trial Manager: 
Dr Anjali Shah

Recruitment Progress:

216
0

Date of latest recruit:

No date given

Site of latest recruit:

No site given
  • SITU Logo
  • OCTRU Logo
  • NDORMS Logo
  • University of Oxford Logo
  • Nottingham Logo
  • Funded by NIHR Logo
Regulatory Information

Sponsor: 
University of Oxford

Funder: 
National Institute for Health and Care Research (NIHR) 
Efficacy and Mechanism Evaluation (EME)
NIHR134096

IRAS: 324901

REC ref: 25/NI/0081

Contact Us

Email:   
geko@ndorms.ox.ac.uk

Telephone: 
07584 887142

Bluesky: 
@geko-study.bsky.social

Address:  
GEKO      
SITU     
Botnar Research Centre      
Windmill Road, Oxford  
OX3 7LD